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PHARMACOLOGY · LOCAL ANESTHETICS

Minutes after a large-volume regional block, a patient reports perioral numbness, tinnitus, and a metallic taste. What is the most appropriate next step?

A Continue the block and reassess in 5 minutes
B Stop the injection and prepare 20% lipid emulsion
Correct. Perioral numbness, tinnitus, and a metallic taste are early signs of local anesthetic systemic toxicity — stop the injection and start 20% lipid emulsion.
C Administer a beta-blocker for the tinnitus
D Increase the local anesthetic dose
Cited source · ASRA Practice Advisory on LAST (2018)
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JKJake Karel, CAA — founder of MACPrep
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“I built MACPrep because board prep for our field was either outdated, uncited, or overpriced. Every question is written and reviewed by a practicing clinician — journal-sourced, with a rationale for every answer choice. It's the resource I wish I'd had for my own boards, and the tool I use to teach the SAAs I precept between cases.”

— Jake Karel, CAA · Founder, MACPrep LLC
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Operating room with an anesthesia team
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